TMOD-21. DEFINING THE GROWTH FACTOR NICHE THAT SUPPORTS GBM INITIATION
نویسندگان
چکیده
منابع مشابه
Osteoblastic niche supports the growth of quiescent multiple myeloma cells.
The heterogeneity of multiple myeloma (MM) contributes to variable responses to therapy. In this study, we aim to correlate the heterogeneity of MM to the presence of quiescent cells using the PKH26 dye. We tracked the rare quiescent cells in different niches of the bone marrow by allowing the cells to cycle in vivo. Surprisingly, quiescent PKH(+) MM cells prefer to reside within the osteoblast...
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ژورنال
عنوان ژورنال: Neuro-Oncology
سال: 2016
ISSN: 1522-8517,1523-5866
DOI: 10.1093/neuonc/now212.891